Advances in the treatment of neurodegenerative diseases (NDs) are nominal. Currently available therapies are merely symptomatic treatments that cannot prevent the development of the disease. Several herbs have been found very useful for managing neurological diseases. There are immense possibilities to discover a more successful line of ND treatment. Phytochemicals from medicinal plants may play a vital role in maintaining the chemical balance of the brain by affecting the capacity of receptors for the major inhibitory neurotransmitters. A few plants have already gained popularity for the potential treatment of NDs. This volume highlights the therapeutic role of medicinal plants and their scientific validation for improving neuronal health. It presents 15 chapters that cover the herbal treatment of NDs, including Parkinson’s disease and Alzheimer’s disease. The contents cover a range of pharmaceutical agents like sirtuins, berberine, rosmarinic acid and resveratrol. The book serves as a reference for pharmacology and herbal medicine scholars as well as healthcare workers interested in information about alternative and complementary therapies for neurological disorders.

Despite an increase in life expectancy over the past 20 years, the number of novel, multi-drug resistant microorganisms has also risen dramatically. To reduce the risk of reemerging infections, and limit the spread of multidrug resistant microorganisms, it is urgently necessary to develop safe and effective therapeutic countermeasures. New antimicrobial chemicals are mostly produced with the help of microorganisms, and the bulk of medications now on the market are of this type. The use of high therapeutic screening and recent developments in analytical instrumentation has allowed the researchers to identify novel antimicrobial compounds from bacteria, fungi, plants, mushrooms, algae, and other sources more quickly. The second volume of Frontiers in Antimicrobial Agents highlights the ongoing requirement for researching and creating novel antimicrobial medications. Current Trends in the Identification and Development of Antimicrobial Agents aims to bring together the expertise of notable academics to examine all facets of antimicrobial research while keeping recent advancements in perspective. Antibiotic discovery, sources of novel antimicrobial chemicals, developing and reemerging microbial infections, various elements of drug resistance, and the need for antimicrobial medications in the future are all covered in this book. It is a timely reference for anyone involved in the discovery and development of new drugs, including microbiologists, biotechnologists, pharmacologists, doctors, and researchers.

This book explores the different ways sleep medicine is practiced in the world by presenting information from multiple countries from all continents. The editors, all sleep medicine experts, dive into both clinical practice, and research keeping an eye on healthcare needs and disparities, before proposing solutions. The contributions also take into account the social, geographical and political situation of each country, along with demographic considerations such as income levels, adding a dimension of context to the contents. The book is meant to be a reference for sleep medicine practitioners who encounter diverse patients in their daily practice. It also serves as a good resource for anyone interested in the state of global health studies.

Recent Trends and the Future of Antimicrobial Agents provides a significantly expanded overview of the topic with updated research in a broader context on the development of alternative approaches against microbial infections. This part consists of ten chapters. The first five chapters describe naturally derived antimicrobial compounds such as plant-based antimicrobials (PBAs), enzymes-based and antibody-based antibacterial therapeutic and secondary metabolites from plant endophytes. The book proceeds to provide details about antimicrobials derived from marine microorganisms (bacteria, fungi, actinomycetes, and cyanobacteria) is included to inform readers about effective medications against MDR strains. Specific chapters describe the drug development against protozoans, with one chapter focusing on Plasmodium. Chapter contributors have postulated novel approaches for antimalarial therapeutics. The book also includes an explanation of host target identification and drug discovery with the purpose of informing the reader about the implications in viral biology and how they could be exploited for treating viral diseases. The contents cater to the information needs of professionals and learners in academia, industry and health services who aim to learn the most significant experimental and practical approaches towards finding alternatives to existing antimicrobial therapies.

Triple negative breast cancers (TNBC) are a biologically aggressive form of breast cancer and constitute approximately 10-15% of all breast cancer patients. Distant metastasis, lack of clinically targeted therapies and prognostic markers, makes the disease difficult to treat. Till now not much work has been carried out on this deadly disease. This book provides an overview of TNBC etiology, its treatment strategies and prognostic markers to identify the outcome of standard therapies. Signalling pathways namely cell proliferation, angiogenesis, invasion and metastasis, apoptosis, autophagy and others involved in complicating the disease have been described in the chapters to convey an understanding about the disease mechanisms. All the possible drugs either in pre-clinical or clinical stages have also been mentioned with data that depicts their efficiency in targeting altered genes. The book also introduces the reader to herbal medicine exhibiting high potency to target TNBC, their synthetic analogs used during chemotherapy and their ability to fight against chemoresistance. The concept of phytonanotechnology has also been discussed. The book helps create awareness among a broad range of readers about TNBC. It points to prioritizing the upgradation of health care facilities and re-designing future treatment strategies to provide maximum benefit to breast cancer patients.

In this third year of the SARS-CoV-2 pandemic responsible for COVD-19 and related diseases worldwide, the scientific studies and reviews focused on this virus and its variants are still crucial. The third volume of the Coronaviruses series brings together some essential data regarding the origin, pathology and chemotherapeutic drugs to treat coronavirus infections. Contributions are written by experienced researchers with the goal of updating medical researchers and clinicians dealing with COVID-19 patients. It presents seven chapters covering a range of topics: (1) bat coronaviruses in the world, (2) hospital challenges during the COVID-19 pandemic, (3) the pro-inflammatory and thrombotic manifestations and the therapeutic options of Covid-19, (4) the common and rare dermatologic manifestations registered in COVID-19 patients, (5) the circulating biomarkers of cardiopulmonary disturbances in COVID-19, and (6) the aspects of pathology and pathogenesis of coronavirus infection

Scientific Philosophy and Principles in Medicine is an accessible treatise on the philosophy that guides medical practice. It lays the foundation of a multidisciplinary framework behind the development of the medical profession. The book presents 10 chapters that cover issues that are frequently encountered by medical professionals in their career: philosophical and linguistic principles of rational thought, scientific, crisp and fuzzy logic, diagnostic aspects, the history of medicine, epistemological concepts, approximate reasoning, principles of medical wisdom, numerical and graphical diagnostics, and the collaboration of researchers involved in the fields of engineering and medicine. The author of the book brings several years of teaching experience and medical practice into this reference with the goal of integrating principles of scientific philosophy and logic into medical education. Readers will understand the process of devising rational diagnostic and treatment approaches that support human health as a generative process that seeks to solve problems through creativity, rather than a classical process of following medical protocols. This book is intended as a basic reference for medical students, teachers, and general readers interested in the application of logic, philosophy and scientific principles in medicine.

This handbook provides an introduction to COVID-19 and herbal medications that boost the human immune system against SARS-CoV-2. The topics are covered in 7 chapters starting with an introduction to the disease, followed by notes on nutraceuticals and common herbal medicines that have therapeutic potential by enhancing the patient's immune response. Special topics such as COVID-19 risk factors and Indian traditional medicines are also included to supplement the contents. The editors have taken advantage of the vast body of knowledge accumulated since the start of the COVID-19 pandemic in 2019. Chapters are written in simple language with structured headings to facilitate a quick understanding of the subject. References are provided for scholars interested in further readings. The book is a quick guide on immune boosting medicines for a broad audience that includes general medical practitioners, nurses, caregivers, and public healthcare workers involved in clinics working in local communities.

In recent years, we have witnessed significant advances in obstetric anesthesia, providing greater safety for the mother and the fetus, as well as an improvement in pain management procedures during labor. This volume presents updates in obstetrics and gynecology that are reflective of the changes in the demographics and associated clinical presentations of gynecological pathologies. It compiles state of the art information on the subject in 20 chapters contributed by more than 50 experts in obstetric anesthesia. The main objective of this volume is to inform and update readers about the different aspects essential to the practice of anesthesia and analgesia during pregnancy, labor, cesarean section and puerperium. The contents also include information about the management of pregnant women with different pathologies and high-risk pregnancies. The authors believe that it is essential for all anesthesiologists to be aware of the latest advances and well-contrasted scientific evidence that will allow them to carry out their usual clinical activity. The volume approaches the subject in a clear and didactic way for the benefit of all professionals involved in this field, including anesthesiologists, gynecologists, obstetricians, surgeons, clinicians and allied healthcare service providers.

This book gives an overview of innovative approaches in telehealth and telemedicine. The Goal of the content is to inform readers about recent computer applications in e-health, including Internet of Things (IoT) and Internet of Medical Things (IoMT) technology. The 9 chapters will guide readers to determine the urgency to intervene in specific medical cases, and to assess risk to healthcare workers. The focus on telehealth along with telemedicine, encompasses a broader spectrum of remote healthcare services for the reader to understand. Chapters cover the following topics: - A COVID-19 care system for virus precaution, prevention, and treatment - The Internet of Things (IoT) in Telemedicine, - Artificial Intelligence for Remote Patient Monitoring systems - Machine Learning in Telemedicine - Convolutional Neural Networks for the detection and prediction of melanoma in skin lesions - COVID-19 virus contact tracing via mobile apps - IoT and Cloud convergence in healthcare - Lung cancer classification and detection using deep learning - Telemedicine in India This book will assist students, academics, and medical professionals in learning about cutting-edge telemedicine technologies. It will also inform beginner researchers in medicine about upcoming trends, problems, and future research paths in telehealth and telemedicine for infectious disease control and cancer diagnosis.