This reference summarizes recent advancements in knowledge about cardiovascular disease and pharmacology. The goal of the book is to inform readers about recent findings on cardiovascular therapeutics and how to conduct experiments to evaluate natural products. It presents 10 chapters that cover basic clinical research on cardiovascular diseases and therapeutic agents derived from natural sources. The book concludes with a series of experiments that demonstrate the methods to test the ameliorative effects of 3 phytochemicals: Biochanin A (red clover), Zingiberene (ginger oil) and Betaine (sugar beet). Key Features - 10 chapters that highlight recent research cardiovascular medicine and pharmacology - Covers knowledge about basic cardiovascular physiology, congestive heart failure treatment and the treatment of heart inflammation. - Covers uses, benefits, and drawbacks of numerous rodent and non-rodent animal models for studying CVD - Updates readers about 21st-century CRISPR-cas9 technology and its uses in CVD. - Covers the significance of Indian Ayurvedic techniques on the cardiovascular system, - Covers information about nutraceuticals for CVD therapy - Includes experiments to evaluate 3 phytochemicals for the treatment of different heart diseases such as hypertension, obesity-cardiomyopathy and the mitigation of inflammatory cytokines in myocardial infarction. This book is an informative resource for cardiologists, and researchers working in the field of cardiovascular pharmacology. It also helps readers to understand the benefits of herbal medications that are commonly available for consumption in homes.

New Findings from Natural Substances present the state-of-the-art and future prospects for the application of biomolecules in the pharmaceutical, agricultural, food and industrial sectors. The book presents eight reviews contributed by more than twenty experts on interesting natural substances, and plant sources, that serve as sources of natural remedies for a variety of ailments. The reviews in the book cover the use of herbs like Heliotropium and Astragalus. Additional health benefits of extracts from essential oils, Caenorhabditis elegans, and olive oil, as well as the medicinal use of rosmarinic acid and hydrolates. The contributions highlight a range of pharmacological agents from natural sources that have anti-cancer, anti-inflammatory, cardioprotective and neuroprotective effects. The contents are presented in a simple and organized style. The book will broaden the knowledge about biological products for a variety of readers - generalists, students and researchers, alike.

This textbook summarizes preliminary knowledge of bioactive molecules which serve as pharmaceuticals, their use, synthesis and mode of action, as well as the production of commercial constituents such as ethanol, citric acid, antibiotics, amino acid, and vitamins. The text is written mainly for the undergraduate and graduate levels of study of all Indian universities according to the recently implemented CBCS curriculum in a simple manner while keeping postgraduate course structures in view. Key Features: Simple structured layout suitable for learners - Considers the CBCS curriculum for Indian Institutions - Covers the subject in 2 parts (Part A: Pharmaceutical Chemistry, Part B: Production) - Covers several types of pharmaceuticals used in clinical practice - Covers the fermentation process and the production of antibiotics, pharmaceutical commodities, and nutrients - Includes an appendix for handy information

This book details all the intricacies and essential knowledge involved in the research and development of the Coronil Kit - a combination of 3 ayurvedic medications for the common cold. It informs the reader about the huge potential of herbal drugs in fighting against any type of disease through evidence-based data from clinical trials and experiments. The book elaborates how current scientific techniques can be applied to understand the healing capacities of plants at their molecular level and thus utilize their different combinations to treat diseases by targeting harmful micro-organisms and simultaneously boosting the immune system. It covers methods of virtual screening and computational validation of identified phytochemicals as potential antiviral agents against the SARS-CoV-2 virus. 70 colored figures. Key Features: 1. Covers the molecular etiology of COVID-19 virus, 2. Covers guidance on drug formulation, hazard assessment, and clinical trials based on approved methods by regulatory organizations 3. Covers pharmacological, toxicological, and technically verified chemical composition of medicinal plants 4. Includes information about in vivo experiments and analysis of Humanoid Zebrafish trials 5. Includes methods of identifying antiviral agents against the SARS-CoV-2 virus 6. Includes chemical, analytical and technical studies of Coronil 7. Includes 70 images 7 chapters 8. Includes a bibliography and appendix The book is primarily intended as a primary resource for medical research scholars and researchers in pharmaceutical companies and as a secondary resource for B.A.M.S. students, medical postgraduate students, and Ayurveda enthusiasts.

This reference summarizes information about pharmaceuticals that can target infectious strains of coronaviruses to neutralize infections. Chapters focus on SARS-CoV-2, drug discovery methods and natural methods to combat the virus, which is a causative agent of COVID-19. Specifically, the book presents 5 chapters written by expert scholar on the following topics: Structure-Based Drug Discovery Approaches Applied to SARS-CoV-2 (the causative agent COVID- 19) Potential Antiviral Medicinal Plants against Novel SARS-CoV-2 Infections Caused by SARS Coronaviruses: Main Characteristics, Targets and Inhibitors Natural Sourced Traditional Indian and Chinese Medicines to Combat COVID- 19 Peptidomimetic and Peptide-Derived Agents Against 3CLpro from Coronaviruses The book contents present both conventional drug design and traditional approaches to discovering relevant drugs in an easy-to-read approach, which is supplemented by bibliographic references. It is intended as a reference for students (pharmacology, pharmacy) and researchers (virology) who are seeking information about antiviral drugs that can be used against coronaviruses.

Frontiers in Clinical Drug Research - Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research - Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology. The fifth volume of this series features 7 reviews with a focus on thalassemia treatment and preeclampsia among other topics. - Recent advances in the diagnosis and management of pulmonary embolism - An evidence-based approach to treatment with iron chelators in transfusion- dependent thalassemia patients: present trends and future scenario - Current and future treatments of iron overload in thalassemia patients - Preeclampsia: biological and clinical aspects - Haematological modulations by fixed dose combination (FDC) of tramadol hydrochloride/paracetamol (THP) - Possible use of eculizumab in critically ill patients infected with covid-19 role of complement c5, neutrophils, and nets in the induction DIC, sepsis, and MOF hematological markers - Emerging diagnostic and therapeutic targets in preeclampsia

Beta-glucan is a polysaccharide and an important food supplement that strengthens the immune system. Beta-glucan can be obtained from many food sources such as mushrooms, yeast, or oats. Beta-glucan has a therapeutic use in the treatment of many diseases, thanks to its immune system strengthening effect. Its use helps curtail the need for administering high levels of antibiotics in case of serious infections. This book presents information about the medical applications of beta-glucan. Starting with an introduction to the basic biochemistry and classification of beta-glucan, the contents explain the readers about its use in treating a variety of medical conditions. These include cancer, allergies, COVID-19, respiratory tract infections, hypercholesterolemia, diabetes and many other other endocrinological, immunological and infectious diseases. This book is a comprehensive resource about the medical use of beta-glucan where any reader can find topical information and learn about recent studies on the therapeutic effects of beta-glucan on the treatment of different diseases.

Burns can cause life-threatening injury and the lengthy hospitalization and rehabilitations required in burn therapy lead to higher healthcare costs. The risk of infection has also been one of the important concerns of burn wound management. The purpose of the burn wound care management is speedy wound healing and epithelization to limit the infection. The topical application of therapeutic agents is quintessential for the longevity of patients having significant burns. In recent times, research on herbal medicine for burn wound management has been vastly increased because of their safer toxicological profiles in contrast to synthetic medicines. Despite the promising therapeutic potential of herbal medicines in this area, herbal medications have some limitations which include low pharmacological activity, solubility and stability. Nanotechnology-based smart drug delivery approaches which involve the use of small molecules as nanocarriers, however, can help to overcome these biopharmaceutical challenges. This book provides an overview of plant-mediated metallic nanoparticulate systems and nanophytomedicine based therapeutic treatment modalities for burn wound lesions. Nine chapters deliver updated information about nanomedicines for burn wound therapy. Contributions are written by experts in nanomedicine and phytomedicine and collectively cover the pathophysiology of wound lesions, current and future outlook of nanomedicine based treatments for burn wound lesions, the role of biocompatible nanomaterials in burn wound management, plant-mediated synthesis of metal nanoparticles for treating burn wound sepsis, phytomedicine based nanoformulations and the phyto-informatics models involved in the wound healing process which are used to select appropriate nanotherapeutic agents. This reference serves as an accessible source of information on the topic of nanomedicine for burn treatments for all healthcare professionals (medical doctors, nurses, students trainees) and researchers in allied fields (pharmacology, phytomedicine) who are interested in this area of medicine.

Herbal Medicine: Back to the Future compiles expert reviews on the application of herbal medicines (including Ayurveda, Chinese traditional medicines and alternative therapies) to treat different ailments. The book series demonstrates the use of sophisticated methods to understand traditional medicine, while providing readers a glimpse into the future of herbal medicine.

Volume 5 continues the theme of the previous volume by featuring reviews of plant based therapies useful for treating different infectious diseases. Topics in this volume are of general interest to computational chemistry researchers, physicians and a broad range of allied healthcare practitioners. Other highlights of this volume include contributions about COVID-19, and traditional medicine in Algeria and China. The topics included in this volume are:

- Improving curcumin and eugenol through computational chemistry and nanotechnology

- Herbal remedies for respiratory tract infections

- COVID-19 pandemic: a comprehensive overview of epidemiological, pathogenesis, diagnostic aspects and therapeutic interventions to tackle current outbreak

- Application of mid-infrared spectroscopy on therapeutic effects of herbal medicine in infectious diseases

- Traditional herbal uses from Algerian pharmacopoeia against infectious diseases

- Traditional Chinese medicine for treating infectious diseases: history, progress, and perspectives

This volume is essential reading for all researchers in the field of natural product chemistry and pharmacology. Medical professionals involved in internal medicine who seek to improve their knowledge about herbal medicine and alternative therapies for tropical and other infectious diseases will also benefit from the contents of the volume.

Cardiac Care and COVID-19: Perspectives in Medical Practice is an accessible reference on diagnoses and treatment modalities for cardiac diseases in general, and emergency cardiac conditions to be more specific, with respect to the current COVID-19 pandemic. Chapters in the book give updated descriptions of common problems in emergency medicine and cardiovascular disease. Each chapter is dedicated to a specific cardiovascular disease and explains management principles, diagnostic procedures and therapy. Examples of medical cases have also been used to highlight complex issues to give a concrete understanding of the cardiac care in COVID-19 patients to the medical practitioner, whether they are involved in critical care or in outpatient clinics. Key Features: - Clinical guidelines for critical care and cardiovascular management of COVID-19 patients - Topic-based information about cardiovascular diseases - Covers a range of cardiovascular problems including myocarditis, arrhythmias, chest pain, acute coronary syndrome - Information on pulmonary embolism and associated problems - Reader friendly presentation - Case-based examples for explaining concepts The range of topics combined with the simple presentation make this an essential reference for healthcare workers in emergency medicine, cardiology and nursing. General physicians interested in the cardiovascular impact of COVID-19 will also benefit from the information provided in the book.