This reference summarizes information about pharmaceuticals that can target infectious strains of coronaviruses to neutralize infections. Chapters focus on SARS-CoV-2, drug discovery methods and natural methods to combat the virus, which is a causative agent of COVID-19. Specifically, the book presents 5 chapters written by expert scholar on the following topics: Structure-Based Drug Discovery Approaches Applied to SARS-CoV-2 (the causative agent COVID- 19) Potential Antiviral Medicinal Plants against Novel SARS-CoV-2 Infections Caused by SARS Coronaviruses: Main Characteristics, Targets and Inhibitors Natural Sourced Traditional Indian and Chinese Medicines to Combat COVID- 19 Peptidomimetic and Peptide-Derived Agents Against 3CLpro from Coronaviruses The book contents present both conventional drug design and traditional approaches to discovering relevant drugs in an easy-to-read approach, which is supplemented by bibliographic references. It is intended as a reference for students (pharmacology, pharmacy) and researchers (virology) who are seeking information about antiviral drugs that can be used against coronaviruses.

New Findings from Natural Substances present the state-of-the-art and future prospects for the application of biomolecules in the pharmaceutical, agricultural, food and industrial sectors. The book presents eight reviews contributed by more than twenty experts on interesting natural substances, and plant sources, that serve as sources of natural remedies for a variety of ailments. The reviews in the book cover the use of herbs like Heliotropium and Astragalus. Additional health benefits of extracts from essential oils, Caenorhabditis elegans, and olive oil, as well as the medicinal use of rosmarinic acid and hydrolates. The contributions highlight a range of pharmacological agents from natural sources that have anti-cancer, anti-inflammatory, cardioprotective and neuroprotective effects. The contents are presented in a simple and organized style. The book will broaden the knowledge about biological products for a variety of readers - generalists, students and researchers, alike.

Bioactive Phytochemicals from Himalayas: A Phytotherapeutic Approach covers herbal medicines from the Himalayan mountains. Chapters in this book detail molecular mechanisms and experimental tools and techniques for research on plants in this region. Phytochemical experts guide the readers through the role of Himalayan plants in therapy for metabolic diseases like cancer and diabetes, hepatic diseases, inflammatory diseases, and neurodegenerative diseases. Some chapters focus on diseases and how various plants from Himalayan origin are beneficial in these diseases. This compilation,with professional contributors, aims to inform a wide scientific community from various research fields about basic research on medicinal plants with a focus on Himalayan herbs. The book also serves as a handbook for pharmacologists working on the broad therapeutic aspects of these plants.

This book explains key concepts and applications of nanotechnology in clinical medicine and pharmacology. The chapters have been contributed by experts and provide a broad perspective about the current and future developments in pharmacology, toxicology, cell biology, and materials science. The book is divided into 2 main sections. The first section concerns nanobiotechnology for human health including gastrointestinal disease, kidney diseases, pulmonary disorders, reproductive system, COVID-19, and cancer. The second section is devoted to toxicological aspects of nanomaterials which involve toxicological assessments of nanotherapeutics and potential solutions for nanotoxicology. Key Features - Emphasizes the high degree of interdisciplinary research in pharmacology, toxicology and nanoscience - Summarizes the results of theoretical, methodological, and practical studies in different medical subspecialties - includes special topics such as novel nanotoxicology assessment methods and nano vaccines - Includes references for further reading

Natural products have dominated our lives since ancient times. Today, they are an inexhaustible source of new medications for disease treatment. The practice of evaluating bioactive compounds extracted from natural sources has also advanced significantly, prompting a need to understand current methods to identify and evaluate them. This book covers basic scientific aspects of preclinical research on natural products for specific conditions and diseases. These include aging, gynecological disorders, inflammatory disorders, renal disorders and cardiovascular disorders. Each of the 10 book chapters give a structured overview on preclinical methods on the etiology of diseases, natural products as the materials for the bioassays, extract types, concentration of the extracts/compounds for in vitro and in vivo assays, preparation of the test materials, application of the test materials, step-by-step methods and related calculations. The book is intended as a quick reference for natural product researchers, pharmacists and postgraduate students in pharmacognosy. Medical doctors working in preclinical research on natural products will also benefit from the information provided.

Practice and Re-emergence of Herbal Medicine focuses on current research in Indian traditional medicine. Chapters cover many facets of herbal medicine, including quality control and experimental validation, intellectual property issues, pharmacovigilance and the therapeutic use of herbal medicine. The book informs readers about the effectiveness of traditional medicine systems, like Ayurveda and Siddha, in the region with reference to specific communities. The book also highlights herbal medications for diseases such as COVID-19, cancer and erectile dysfunction. The book is a timely reference for researchers interested in ethnobotany, alternative medicine and the practice of herbal medicine in indigenous communities. Series Introduction: Natural Medicine is a series of edited volumes that aims to be a repository of knowledge on herbal and traditional medicine with the goal of attracting a global audience. Contributions to the series will present evidence of the efficacy of plant-based medicine against disease. The series will also highlight issues in herbal medicine practice and research.

New Avenues in Drug Discovery and Bioactive Natural Products is the second volume of the Natural Medicine book series. It is devoted to current research in drug discovery from natural sources. The volume features 13 chapters that cover modern analytical and scientific approaches. The book starts with chapters on advanced analytical and research techniques, such as genomic mining, quality control of herbal drugs, DNA fingerprinting, high-throughput screening, molecular docking and extraction techniques. The contributors provide a summary of challenges for researchers and commercial applications where possible. The book also features chapters dedicated to specific medicinal agents that target a disease (glycosides, SARS-CoV2 spike protein inhibitors, and andrographolides. The collection of important research topics in natural product chemistry aims to help the scholars and researchers in the scientific community that are involved in the extraction and development of new medicines.

Chromene is a naturally abundant heterocyclic compound found in alkaloids, tocopherols, terpenes and other compounds. Its derivatives can be used as a scaffold that exhibits pharmacological activity in the human body. Chromene drugs and related bioactive molecules are the prime focus of this reference. It presents 13 thoroughly researched chapters that comprehensively cover all aspects about the molecule. Starting with a detailed introduction to its role and importance in drug discovery, the book goes into the details of chromene structure, synthesis and pharmacology. Readers can gain knowledge of different commercial medicines based on chromene and its pharmacological activity against different diseases. The elaborate topics in the book will help researchers working on chromene based drugs. Key highlights of the book include: - Complete coverage of chromene's role in nature and drug development with references to historical background and current developments - References to commercial and preclinical drugs and patents of interest - Explanation of chromene bioacivity in different diseases (antioxidant, antidiabetic, antinflammatory, antibacterial and antifungal activities, antitumour, immunomodulatory activity) - Explanation of chromene activity against SARS-Cov2

Plant-derived Hepatoprotective Drugs is a comprehensive guide that explores the world of medicinal plants and their hepatoprotective properties, offering both basic and applied insights for scholars and hepatology residents. Structured chapters provide a deep dive into the subject, while referencing relevant research and future perspectives. Readers will learn the science behind hepatotoxicity and the role of plants in safeguarding liver health. The book also helps researchers to explore bioactive compounds extracted from plants, along with herbal formulations that contribute to hepatoprotection, and conveys an understanding of the effects of edible plants and spices on liver wellness. A chapter focusing on isolation and characterization of phytochemicals bridges theory and application for discovering and developing hepatoprotective biopharmaceuticals. Key Features: Gives a thorough understanding of hepatotoxicity and related bioactive compounds Comprehensive references to enhance understanding Well-structured chapters providing organized knowledge Basic and applied information for diverse readers Future perspectives offering a glimpse into ongoing research This is an ideal reference for pharmacology scholars and residents in hepatology, as well as readers interested in nature's potential in promoting liver health.

Advanced Pharmacy is a textbook dedicated to advanced applications in pharmacy. The book balances information by including chapters that give basic knowledge and inform readers on the latest insights in pharmaceutical science. Authored by pharmacology experts and academics, each chapter highlights current knowledge in the field, presenting research in a didactic and educational manner for academics, researchers, and students who need to understand pharmacy. Additional features of the book include chapter summaries and references for advanced readers. Topics: Physical Pharmacy: Covers foundations of physical pharmacy, providing a solid understanding of the subject. Preformulation Studies: examines active pharmaceutical ingredient-excipent compatibility studies, a crucial aspect of drug formulation. Medicinal Chemistry Applications: explores medicinal chemistry applications using QSAR/QSPR theory. Computer-assisted Study: explains computer-assisted studies with the example of garlic organosulfur as an antioxidant agent. Enzymes in Biocatalysis: sheds light on enzyme characteristics, kinetics, production, and applications in biocatalysis. Antifungal Agents: provides insights into antifungal agents and their significance. Polysaccharides in Drug Delivery: explores the use of naturally and chemically sulfated polysaccharides in drug delivery systems. Immunomodulatory Plant Extracts: covers the evaluation of safety and benefits of immunomodulatory plant extracts. Biofilms and Persistent Cells: examines the development, causes, and consequences of biofilms and persistent cells. Analytical Methods for Drug Analysis: focuses on the development of analytical methods for analyzing drugs of abuse using experimental design. Steric Exclusion Chromatography: discusses steric exclusion chromatography, including chromatography of polymers in aqueous solutions. Intrinsic Viscosity Methods: explores intrinsic viscosity methods in natural polymer pharmaceutical excipients. Extraction Techniques in Green Analytical Chemistry: highlight environment-firendly techniques in analytical chemistry. Advanced Pharmacy is a comprehensive resource that bridges the gap between pharmaceutical research and practice, offering invaluable insights into the latest developments in the field. This textbook serves as an essential reference for both learners and scholars in basic and advanced courses in pharmacy and pharmaceutical science.