This reference summarizes recent advancements in knowledge about cardiovascular disease and pharmacology. The goal of the book is to inform readers about recent findings on cardiovascular therapeutics and how to conduct experiments to evaluate natural products. It presents 10 chapters that cover basic clinical research on cardiovascular diseases and therapeutic agents derived from natural sources. The book concludes with a series of experiments that demonstrate the methods to test the ameliorative effects of 3 phytochemicals: Biochanin A (red clover), Zingiberene (ginger oil) and Betaine (sugar beet). Key Features - 10 chapters that highlight recent research cardiovascular medicine and pharmacology - Covers knowledge about basic cardiovascular physiology, congestive heart failure treatment and the treatment of heart inflammation. - Covers uses, benefits, and drawbacks of numerous rodent and non-rodent animal models for studying CVD - Updates readers about 21st-century CRISPR-cas9 technology and its uses in CVD. - Covers the significance of Indian Ayurvedic techniques on the cardiovascular system, - Covers information about nutraceuticals for CVD therapy - Includes experiments to evaluate 3 phytochemicals for the treatment of different heart diseases such as hypertension, obesity-cardiomyopathy and the mitigation of inflammatory cytokines in myocardial infarction. This book is an informative resource for cardiologists, and researchers working in the field of cardiovascular pharmacology. It also helps readers to understand the benefits of herbal medications that are commonly available for consumption in homes.

This book gives an overview of innovative approaches in telehealth and telemedicine. The Goal of the content is to inform readers about recent computer applications in e-health, including Internet of Things (IoT) and Internet of Medical Things (IoMT) technology. The 9 chapters will guide readers to determine the urgency to intervene in specific medical cases, and to assess risk to healthcare workers. The focus on telehealth along with telemedicine, encompasses a broader spectrum of remote healthcare services for the reader to understand. Chapters cover the following topics: - A COVID-19 care system for virus precaution, prevention, and treatment - The Internet of Things (IoT) in Telemedicine, - Artificial Intelligence for Remote Patient Monitoring systems - Machine Learning in Telemedicine - Convolutional Neural Networks for the detection and prediction of melanoma in skin lesions - COVID-19 virus contact tracing via mobile apps - IoT and Cloud convergence in healthcare - Lung cancer classification and detection using deep learning - Telemedicine in India This book will assist students, academics, and medical professionals in learning about cutting-edge telemedicine technologies. It will also inform beginner researchers in medicine about upcoming trends, problems, and future research paths in telehealth and telemedicine for infectious disease control and cancer diagnosis.

Scientific Philosophy and Principles in Medicine is an accessible treatise on the philosophy that guides medical practice. It lays the foundation of a multidisciplinary framework behind the development of the medical profession. The book presents 10 chapters that cover issues that are frequently encountered by medical professionals in their career: philosophical and linguistic principles of rational thought, scientific, crisp and fuzzy logic, diagnostic aspects, the history of medicine, epistemological concepts, approximate reasoning, principles of medical wisdom, numerical and graphical diagnostics, and the collaboration of researchers involved in the fields of engineering and medicine. The author of the book brings several years of teaching experience and medical practice into this reference with the goal of integrating principles of scientific philosophy and logic into medical education. Readers will understand the process of devising rational diagnostic and treatment approaches that support human health as a generative process that seeks to solve problems through creativity, rather than a classical process of following medical protocols. This book is intended as a basic reference for medical students, teachers, and general readers interested in the application of logic, philosophy and scientific principles in medicine.

Alzheimer’s disease (AD) is currently recognized as an untreatable, progressive, degenerative and terminal disease that is globally afflicting an estimated 36 million people and this number is growing in an unabated and frightening manner. Advances in Alzheimer Research, provides researchers with an integrated approach to AD academic literature ranging from basic to advanced clinical research. The series highlights the latest information in order to unravel the origin, pathogenesis and prevention of AD. The purpose of this book series is, therefore, to capture and discuss both, improvements towards the diagnosis and potential treatment of AD by established and novel strategies. This first volume of the series provides an important mechanism to bring individuals having a variety of scientific interests and expertise under one roof to specifically focus on AD and related dementias. This volume presents articles on beta amyloid protein targets as well as research on secretase enzyme systems among other topics that deal with AD therapy.

Alzheimer’s disease (AD) is currently recognized as an untreatable, progressive, degenerative and terminal disease that is global – afflicting over 36 million people worldwide, with the number growing in an unabated and frightening manner. The goal of the series Advances in Alzheimer’s Research , with Volumes 1 and 2, is to provide an integrated approach to AD from basic and clinical research and to highlight the valuable information in order to unravel the origin, pathogenesis and prevention of AD. The aim of this book is to both capture and discuss improvements toward the diagnosis and potential treatment of AD by both established and novel strategies. This book series, including the Volume 2, provides an important mechanism to bring under the same roof a variety of scientific interests and expertise to specifically focus on AD and related dementias. The fullest attempt has been made to disseminate the most current knowledge on recent advances in potential therapy of AD.

This book provides a quick update on key aspects of current anesthesia practice. Book chapters are written in a concise manner to enable readers (anesthesia providers and medical students) to quickly refresh their knowledge, and understand the essential points about key topics. The chapters are written by eminent clinicians who are also outstanding teachers in their respective anesthesia training programs. Topics covered in this volume include: trauma, trauma anesthesia, regional anesthesia, upper extremity blocks, lower extremity blocks, ultrasound, the use of ultrasound for blocks and vascular access, coagulation, hemostasis, transfusion, anticoagulants and their reversal, issues in pediatric anesthesia, and pediatric trauma, as well as obstetrical anesthesia. The book serves as a handbook for advanced anesthesia professionals and a textbook for medical students.

This book provides an updated information about major systems for anesthesia in patients with concomitant diseases. Book chapters are designed to allow anesthesia providers to refresh their knowledge, and be able to focus on the current issues in these subspecialty areas. Readers will be able to approach anesthesia cases more effectively with the information provided. The chapters are written by eminent clinicians who are also outstanding teachers in their respective anesthesia training programs. Topics covered in this volume include: thoracic anesthesia, cardiac anesthesia, anesthesia in the ENT patient, neuroanesthesia, intensive care / ICU medicine, medical ethics, and interesting cases. The book serves as a handbook for advanced anesthesia professionals and a textbook for medical students.

In recent years, there have been many advances in the safe management of the patient's airway, a cornerstone of anesthetic practice. An Update on Airway Management brings forth information about new approaches in airway management in many clinical settings. <p></p> This volume analyzes and explains new preoperative diagnostic methods, algorithms, intubation devices, extubation procedures, novelties in postoperative management in resuscitation and intensive care units, while providing a simple, accessible and applicable reading experience that helps medical practitioners in daily practice. The comprehensive updates presented in this volume make this a useful reference for anesthesiologists, surgeons and EMTs at all levels. <p></p> Key topics reviewed in this reference include: <p></p> · New airway devices, clinical management techniques, pharmacology updates (ASA guidelines, DAS algorithms, Vortex approach, etc.), <p></p> · Induced and awake approaches in different settings <p></p> · Updates on diagnostic accuracy of perioperative radiology and ultrasonography <p></p> · Airway management in different settings (nonoperating room locations and emergency rooms) <p></p> · Airway management in specific patient groups (for example, patients suffering from morbid obesity, obstetric patients and critical patients) <p></p> · Algorithms and traditional surgical techniques that include emergency cricothyrotomy and tracheostomy in ‘Cannot Intubate, Cannot Ventilate’ scenarios. <p></p> · Learning techniques to manage airways correctly, focusing on the combination of knowledge, technical abilities, decision making, communication skills and leadership <p></p> · Special topics such as difficult airway management registry, organization, documentation, dissemination of critical information, big data and databases

In recent years, we have witnessed significant advances in obstetric anesthesia, providing greater safety for the mother and the fetus, as well as an improvement in pain management procedures during labor. This volume presents updates in obstetrics and gynecology that are reflective of the changes in the demographics and associated clinical presentations of gynecological pathologies. It compiles state of the art information on the subject in 20 chapters contributed by more than 50 experts in obstetric anesthesia. The main objective of this volume is to inform and update readers about the different aspects essential to the practice of anesthesia and analgesia during pregnancy, labor, cesarean section and puerperium. The contents also include information about the management of pregnant women with different pathologies and high-risk pregnancies. The authors believe that it is essential for all anesthesiologists to be aware of the latest advances and well-contrasted scientific evidence that will allow them to carry out their usual clinical activity. The volume approaches the subject in a clear and didactic way for the benefit of all professionals involved in this field, including anesthesiologists, gynecologists, obstetricians, surgeons, clinicians and allied healthcare service providers.

Triple negative breast cancers (TNBC) are a biologically aggressive form of breast cancer and constitute approximately 10-15% of all breast cancer patients. Distant metastasis, lack of clinically targeted therapies and prognostic markers, makes the disease difficult to treat. Till now not much work has been carried out on this deadly disease. This book provides an overview of TNBC etiology, its treatment strategies and prognostic markers to identify the outcome of standard therapies. Signalling pathways namely cell proliferation, angiogenesis, invasion and metastasis, apoptosis, autophagy and others involved in complicating the disease have been described in the chapters to convey an understanding about the disease mechanisms. All the possible drugs either in pre-clinical or clinical stages have also been mentioned with data that depicts their efficiency in targeting altered genes. The book also introduces the reader to herbal medicine exhibiting high potency to target TNBC, their synthetic analogs used during chemotherapy and their ability to fight against chemoresistance. The concept of phytonanotechnology has also been discussed. The book helps create awareness among a broad range of readers about TNBC. It points to prioritizing the upgradation of health care facilities and re-designing future treatment strategies to provide maximum benefit to breast cancer patients.